Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18610497 | 0.90 | RORC (0.63) | RORCRAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL15775205 | 0.88 | RORC (0.54) | RORCRAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL18585517 | 0.86 | SMN1; SMN2 (0.62) | RAB9ASMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL9232101 | 0.86 | ALOX5 (0.66) | RORCSMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL6866168 | 0.83 | NPC1 (0.71) | RORCRAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL7408604 | 0.81 | HTT (0.49) | RORCRAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL8521515 | 0.81 | MEN1 (0.60) | RORCRAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL14777468 | 0.81 | KMT2A (0.66) | RAB9ASMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL10599217 | 0.81 | MEN1 (0.64) | RAB9ASMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL14075258 | 0.80 | NPC1 (0.59) | RAB9ASMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |
| US-5064862-A | 4-Amino-2*,6*-Dimethylbenzanilide | RESEARCH CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| EP-0213572-B1 | 3-AND 4-AMINO-N(ALKYL PHENYL) BENZAMIDE COMPOUNDS AND COMPOSITION CONTAINING SAME AS ANTICONVULSANT DRUGS | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1991-07-03 | — | — | EP | disclosed |
| EP-0213572-A1 | 3-and 4-amino-N(alkyl phenyl) benzamide compounds and composition containing same as anticonvulsant drugs | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1987-03-11 | — | — | EP | disclosed |
| US-4638014-A | AMINOBENZANILIDES | RESEARCH CORPORATION (US) | 1987-01-20 | — | — | US | disclosed |