Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367686 | 0.81 | RORC (0.63) | HTTSMN1; SMN2LMNAS1PR4RORC | |
| Hydrochloric Acid SCHEMBL9523346 | 0.79 | HDAC3 (0.54) | HTTSMN1; SMN2LMNAS1PR4KDM4E | |
| SCHEMBL9523014 | 0.76 | S1PR4 (0.69) | SMN1; SMN2S1PR4KDM4ERAB9ANPC1 | |
| SCHEMBL9522743 | 0.75 | S1PR4 (0.58) | HTTS1PR4KDM4ERAB9ANPC1 | |
| SCHEMBL4138460 | 0.74 | POLB (0.67) | SMN1; SMN2LMNAS1PR4KDM4ERAB9A | |
| SCHEMBL613081 | 0.74 | HTT (0.49) | HTTSMN1; SMN2S1PR4KDM4ERAB9A | |
| SCHEMBL10599217 | 0.74 | MEN1 (0.64) | HTTSMN1; SMN2LMNAS1PR4RAB9A | |
| SCHEMBL8521515 | 0.74 | MEN1 (0.60) | HTTSMN1; SMN2LMNAS1PR4RORC | |
| SCHEMBL9232101 | 0.74 | ALOX5 (0.66) | HTTSMN1; SMN2LMNAKDM4ERORC | |
| SCHEMBL10602333 | 0.74 | SMN1; SMN2 (0.55) | HTTSMN1; SMN2LMNAS1PR4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |