Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370266 | 0.82 | SMN1; SMN2 (0.44) | KDM4EHPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7374874 | 0.82 | SMN1; SMN2 (0.41) | KDM4EHPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7370168 | 0.82 | KDM4E (0.46) | KDM4EHPGDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7406133 | 0.78 | GRIA1 (0.58) | KDM4EHPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7406142 | 0.78 | GRIA1 (0.58) | KDM4EHPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL27369371 | 0.76 | RAB9A (0.40) | KDM4EHPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7366847 | 0.76 | TSHR (0.41) | KDM4EHPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7370615 | 0.75 | ERCC1 (0.46) | KDM4ESMN1; SMN2MCL1RAB9ANPC1 | |
| SCHEMBL8120929 | 0.75 | MCL1 (0.36) | KDM4EHPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7373678 | 0.74 | NPC1 (0.43) | KDM4EHPGDSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994107-A1 | 5-Arylisoxazol-4-yl-substituted 2-amino carboxylic acid compounds | H. LUNDBECK A/S (DK) | 2000-04-19 | — | — | EP | disclosed |
| EP-0726896-A1 | 5-ARYLISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | H. LUNDBECK A/S (DK) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012587-A1 | 5-ARYLISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | H. LUNDBECK A/S (DK) | 1995-05-11 | — | — | WO | disclosed |