Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 7/20 | 0.53 |
| ▸ | INPP5A | Q14642 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | INPP5B | P32019 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156538 | 0.88 | TAAR1 (0.60) | INPPL1INPP5AKDM4EATMINPP5B | |
| SCHEMBL9156756 | 0.87 | TSHR (0.61) | INPPL1INPP5AKDM4EATMTAAR1 | |
| Hydrochloric Acid SCHEMBL9152256 | 0.85 | LMNA (0.62) | KDM4EATMTAAR1MAPK1TSHR | |
| SCHEMBL17027965 | 0.83 | BACE1 (0.43) | INPPL1INPP5AKDM4EATMINPP5B | |
| SCHEMBL7363469 | 0.79 | POLB (0.57) | INPPL1INPP5AKDM4EATMINPP5B | |
| SCHEMBL6431657 | 0.77 | TAAR1 (0.52) | INPPL1INPP5AKDM4ETAAR1KMT2A | |
| SCHEMBL9237628 | 0.75 | DRD2 (0.51) | KDM4ETSHRCYP3A4NFKB1DRD2 | |
| SCHEMBL7368908 | 0.74 | LMNA (0.46) | TSHRLMNAKMT2AADRA2ADRD2 | |
| SCHEMBL17695712 | 0.73 | SLC7A5 (0.53) | INPPL1INPP5AKDM4EMEN1KMT2A | |
| SCHEMBL17693610 | 0.73 | INPPL1 (0.46) | INPPL1INPP5AKDM4EINPP5BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438047-A | Diphosphates of catecholamines and pharmaceutical compositions containing them | ZAMBON GROUP S.P.A. (IT) | 1995-08-01 | — | — | US | disclosed |
| EP-0607394-A1 | DIPHOSPHATES OF CATECHOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994003461-A1 | DIPHOSPHATES OF CATECHOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.P.A. (IT) | 1994-02-17 | — | — | WO | disclosed |