Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | INPPL1 | O15357 | 5/20 | 0.49 |
| ▸ | INPP5A | Q14642 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fosopamine SCHEMBL828844 | 0.88 | MAPT (0.57) | POLBATMADRA2AADRA2CADRA1A | |
| Fosopamine SCHEMBL30567798 | 0.88 | MAPT (0.57) | POLBATMADRA2AADRA2CADRA1A | |
| SCHEMBL9159471 | 0.88 | MAPT (0.57) | POLBATMADRA2AADRA2CADRA1A | |
| Fosopamine SCHEMBL9152610 | 0.87 | MAPT (0.58) | POLBATMADRA2AADRA2CADRA1A | |
| SCHEMBL7368908 | 0.79 | LMNA (0.46) | ADRA2AADRA2CADRA1AADRB2DRD2 | |
| SCHEMBL7367716 | 0.79 | INPPL1 (0.53) | ATMADRA2AADRA1AADRB2DRD2 | |
| SCHEMBL25486427 | 0.76 | MAPT (0.42) | POLBATMADRA2AADRA2CADRA1A | |
| SCHEMBL10604051 | 0.76 | MAPT (0.53) | POLBATMADRA2AADRA2CADRA1A | |
| SCHEMBL9237628 | 0.75 | DRD2 (0.51) | ADRA1ADRD2DRD1DRD3TSHR | |
| SCHEMBL9152005 | 0.74 | S1PR2 (0.43) | ADRB2DRD2DRD1DRD3INPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438047-A | Diphosphates of catecholamines and pharmaceutical compositions containing them | ZAMBON GROUP S.P.A. (IT) | 1995-08-01 | — | — | US | claimed |
| US-5438047-A | Diphosphates of catecholamines and pharmaceutical compositions containing them | ZAMBON GROUP S.P.A. (IT) | 1995-08-01 | — | — | US | disclosed |
| EP-0607394-A1 | DIPHOSPHATES OF CATECHOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994003461-A1 | DIPHOSPHATES OF CATECHOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.P.A. (IT) | 1994-02-17 | — | — | WO | disclosed |