Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 5/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363469 | 0.79 | POLB (0.57) | LMNASMN1; SMN2ALDH1A1TSHRADRB2 | |
| SCHEMBL7370487 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2CA1CA2 | |
| SCHEMBL7364941 | 0.75 | MAPT (0.65) | LMNASMN1; SMN2CA1CA2CA9 | |
| SCHEMBL28976208 | 0.75 | MAPT (0.65) | LMNASMN1; SMN2CA1CA2CA9 | |
| SCHEMBL30281537 | 0.75 | MAPT (0.65) | LMNASMN1; SMN2CA1CA2CA9 | |
| SCHEMBL15970734 | 0.74 | LMNA (0.61) | LMNASMN1; SMN2CA1CA2CA9 | |
| SCHEMBL7367716 | 0.74 | INPPL1 (0.53) | LMNAALDH1A1TSHRADRB2ADRA2A | |
| SCHEMBL17693610 | 0.74 | INPPL1 (0.46) | ALDH1A1KMT2A | |
| SCHEMBL12246750 | 0.73 | MAPT (0.60) | LMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL12299017 | 0.73 | MAPT (0.69) | LMNASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438047-A | Diphosphates of catecholamines and pharmaceutical compositions containing them | ZAMBON GROUP S.P.A. (IT) | 1995-08-01 | — | — | US | disclosed |
| EP-0607394-A1 | DIPHOSPHATES OF CATECHOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994003461-A1 | DIPHOSPHATES OF CATECHOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.P.A. (IT) | 1994-02-17 | — | — | WO | disclosed |