Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785694 | 0.64 | TLR7 (0.39) | SPHK1 | |
| SCHEMBL23923721 | 0.62 | PTGS2 (0.41) | — | |
| SCHEMBL23924076 | 0.61 | CNR1 (0.45) | — | |
| SCHEMBL24601359 | 0.59 | ALDH1A1 (0.54) | FAAHMGLLCA2 | |
| SCHEMBL10568240 | 0.59 | ESR1 (0.73) | MGLLCA1CA2 | |
| SCHEMBL181089 | 0.59 | ESR1 (0.73) | MGLLCA1CA2 | |
| SCHEMBL3482538 | 0.58 | MGLL (0.97) | FAAHMGLLCA2 | |
| SCHEMBL3395815 | 0.57 | MGLL (1.00) | FAAHMGLLS1PR1 | |
| SCHEMBL8736182 | 0.57 | MGLL (1.00) | FAAHMGLLS1PR1 | |
| SCHEMBL2511615 | 0.57 | ESR1 (0.77) | MGLLCA2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244669-A1 | PYRAZOLOPYRAZINES AND THEIR USE AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001040230-A1 | PYRAZOLOPYRAZINES AND THEIR USE AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-07 | — | — | WO | disclosed |