Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | PTAFR | P25105 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16310778 | 0.89 | TBXAS1 (0.58) | RAB9ANPC1LMNAPTAFRCYP1A2 | |
| SCHEMBL6280463 | 0.87 | GAA (0.65) | RAB9ANPC1GAALMNAKMT2A | |
| SCHEMBL15988693 | 0.85 | LMNA (0.70) | RAB9ANPC1GAALMNAKMT2A | |
| SCHEMBL4093157 | 0.84 | LMNA (0.61) | RAB9ANPC1GAALMNAKMT2A | |
| SCHEMBL11606129 | 0.83 | GAA (0.61) | RAB9ANPC1GAALMNAKMT2A | |
| SCHEMBL9475090 | 0.83 | PLOD2 (0.60) | RAB9ANPC1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6794180 | 0.82 | CHRNA7 (0.53) | RAB9ANPC1LMNACYP1A2ALDH1A1 | |
| SCHEMBL9475946 | 0.82 | GAA (0.53) | RAB9ANPC1GAALMNAKMT2A | |
| SCHEMBL9475952 | 0.82 | GAA (0.53) | RAB9ANPC1GAALMNAKMT2A | |
| SCHEMBL1304210 | 0.82 | NPC1 (1.00) | RAB9ANPC1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993019047-A1 | TETRAHIDROPYRIDINYL (3/4) SUBSTITUED OXIMES HAVING SIGMA RECEPTOR AFFINITY AND THEIR USE IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM CONDITIONS | WARNER-LAMBERT COMPANY (US) | 1993-09-30 | — | — | WO | disclosed |
| US-5208343-A | Antidepressants, antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | disclosed |