Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371036 | 0.88 | CTSS (0.55) | CTSKCTSSTSHRKMT2AATM | |
| SCHEMBL9300286 | 0.87 | TSHR (0.54) | CTSKCTSSTSHRKMT2ASLC6A9 | |
| SCHEMBL7372683 | 0.86 | CTSS (0.57) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7372337 | 0.86 | CTSS (0.57) | CTSKCTSSCTSLCTSB | |
| SCHEMBL13567835 | 0.86 | CTSK (0.53) | CTSKCTSSKMT2AATMCTSL | |
| SCHEMBL7373764 | 0.85 | CTSK (0.58) | CTSKCTSSTSHRKMT2ASLC6A9 | |
| SCHEMBL7367960 | 0.82 | CTSK (0.60) | CTSKCTSSCTSLCTSB | |
| SCHEMBL2009327 | 0.81 | SLC6A9 (0.64) | CTSKCTSSTSHRKMT2ASLC6A9 | |
| SCHEMBL14820895 | 0.80 | CTSK (0.57) | CTSKCTSSTSHRKMT2AATM | |
| SCHEMBL29480433 | 0.80 | CTSK (0.50) | CTSKCTSSKMT2AATMCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027958-A1 | 4-AMIDINOPHENYLSULPHONAMIDES FOR THE TREATMENT OF THROMBO-EMBOLITIC CONDITIONS | BOEHRINGER MANNHEIM GMBH (DE) | 1994-12-08 | — | — | WO | disclosed |