Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394740 | 0.90 | ALDH1A1 (0.56) | TSHRALDH1A1MAPTMEN1KMT2A | |
| Dimethylamine SCHEMBL28428235 | 0.86 | ALDH1A1 (0.51) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1764151 | 0.84 | ALDH1A1 (0.53) | LMNAGAAABCC4TSHRPTGS1 | |
| SCHEMBL28835498 | 0.84 | LMNA (0.55) | LMNAGAAABCC4TSHRPTGS1 | |
| SCHEMBL7696584 | 0.83 | KMT2A (0.50) | LMNAGAAHTTALDH1A1MAPT | |
| SCHEMBL5803357 | 0.82 | CA2 (0.49) | LMNAGAATSHRALDH1A1MAPT | |
| Dimethylamine SCHEMBL4648966 | 0.81 | ALDH1A1 (0.51) | LMNAGAAHTTALDH1A1MAPT | |
| SCHEMBL5300752 | 0.81 | ALOX5 (0.61) | LMNAALDH1A1L3MBTL1 | |
| SCHEMBL6925456 | 0.81 | KMT2A (0.51) | LMNAGAAALDH1A1MAPTMEN1 | |
| SCHEMBL8910636 | 0.81 | MAPT (0.51) | LMNAGAAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110194731-B | Mercaptopropionic acid amide compound, preparation method and medicinal application thereof | 复旦大学 | 2021-05-04 | — | — | CN | disclosed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |