Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.50 |
| ▸ | ECE1 | P42892 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790695 | 1.00 | MME (0.50) | MMEECE1HRH4ACEMEN1 | |
| SCHEMBL7362722 | 0.90 | PPARG (0.49) | MMEECE1HRH4ACEMEN1 | |
| SCHEMBL7366217 | 0.86 | LTA4H (0.44) | MMEECE1HRH4ACEMEN1 | |
| SCHEMBL7362721 | 0.86 | MME (0.44) | MMEECE1HRH4ACEKMT2A | |
| SCHEMBL7316396 | 0.85 | MME (0.53) | MMEECE1HRH4ACE | |
| SCHEMBL10790828 | 0.84 | MME (0.52) | MMEECE1HRH4ACE | |
| SCHEMBL10794359 | 0.84 | KDM4E (0.47) | MMEECE1HRH4ACE | |
| SCHEMBL10789536 | 0.81 | MME (0.49) | MMEECE1HRH4ACE | |
| SCHEMBL7318461 | 0.81 | ACE (0.70) | MMEECE1ACE | |
| SCHEMBL7367811 | 0.81 | ACE (0.70) | MMEECE1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |