Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.32 |
| ▸ | FLT1 | P17948 | 2/20 | 0.31 |
| ▸ | FLT4 | P35916 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28840996 | 0.82 | PGK1 (0.32) | NPC1RAB9ACHRM1CYP3A4LMNA | |
| SCHEMBL28873539 | 0.78 | ALOX15 (0.34) | NPC1RAB9ACLCN2CHRM1TBXA2R | |
| SCHEMBL16019011 | 0.78 | SMN1; SMN2 (0.35) | NPC1RAB9ACLCN2CHRM1TBXA2R | |
| SCHEMBL7924637 | 0.78 | TSHR (0.47) | CLCN2CHRM1TBXA2RCYP3A4ALDH1A1 | |
| SCHEMBL17612257 | 0.76 | ALDH1A1 (0.40) | CLCN2CHRM1TBXA2RCYP3A4ALOX15 | |
| SCHEMBL28881890 | 0.76 | CLCN2 (0.33) | NPC1RAB9ACLCN2CHRM1TBXA2R | |
| SCHEMBL10407716 | 0.76 | CLCN2 (0.44) | RAB9ACLCN2ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL29051212 | 0.73 | CHRM1 (0.35) | NPC1RAB9ACLCN2FLT1FLT4 | |
| SCHEMBL15698329 | 0.72 | GSK3B (0.41) | RAB9AALDH1A1LMNAPTGS2SMN1; SMN2 | |
| SCHEMBL22996048 | 0.69 | CLCN2 (0.36) | CLCN2CHRM1TBXA2RCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223945-A1 | COMPOSITIONS COMPRISING OXOPHOSPHONATE-BASED METALLOPROTEINASE INHIBITORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001026661-A1 | COMPOSITIONS COMPRISING OXOPHOSPHONATE-BASED METALLOPROTEINASE INHIBITORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-04-19 | — | — | WO | disclosed |