Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205144 | 0.83 | PGR (0.85) | PGRLMNAMAPK1GAAKIF11 | |
| SCHEMBL12054668 | 0.82 | KEAP1 (0.75) | PGRLMNAMAPK1GAAKIF11 | |
| SCHEMBL171658 | 0.81 | LMNA (0.79) | PGRLMNAMAPK1GAAKIF11 | |
| SCHEMBL15387008 | 0.79 | PGR (0.61) | PGRLMNAMAPK1GAAKIF11 | |
| SCHEMBL2451476 | 0.79 | PGR (0.71) | PGRLMNAMAPK1GAAKIF11 | |
| SCHEMBL3073466 | 0.79 | NPC1 (0.63) | PGRLMNAMAPK1GAAKIF11 | |
| SCHEMBL7623713 | 0.78 | PGR (0.59) | PGRLMNAMAPK1GAAKIF11 | |
| SCHEMBL321265 | 0.78 | PGR (0.59) | PGRLMNAMAPK1GAAKIF11 | |
| SCHEMBL4668688 | 0.76 | LMNA (0.72) | PGRLMNAMAPK1GAAKIF11 | |
| SCHEMBL3073463 | 0.76 | PGR (0.58) | PGRLMNAMAPK1GAAKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002463-A1 | ANTIHYPERTENSIVE 1,4-DIHYDROPYRIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-03 | — | — | WO | disclosed |