Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | KIF11 | P52732 | 4/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | PLAU | P00749 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171658 | 0.94 | LMNA (0.79) | LMNAGAAMAPK1KIF11CA1 | |
| SCHEMBL3116450 | 0.89 | PGR (0.73) | LMNAGAAMAPK1KIF11CA1 | |
| SCHEMBL31041151 | 0.85 | KIF11 (0.79) | LMNAKIF11CA1CA2PGR | |
| SCHEMBL24689849 | 0.84 | LMNA (0.66) | LMNAGAAMAPK1KIF11CA1 | |
| SCHEMBL3985582 | 0.84 | LMNA (0.76) | LMNAGAAMAPK1KIF11CA1 | |
| Lithium SCHEMBL31041154 | 0.83 | KIF11 (0.76) | LMNAKIF11CA1CA2PGR | |
| SCHEMBL28082142 | 0.82 | RAB9A (0.73) | LMNAGAAMAPK1CA1CA2 | |
| SCHEMBL3468171 | 0.82 | LMNA (0.64) | LMNAGAAMAPK1CA1CA2 | |
| SCHEMBL32679643 | 0.81 | GAA (0.78) | LMNAGAAMAPK1PLAUPGR | |
| SCHEMBL3376915 | 0.80 | PGR (0.90) | KIF11PGRNPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |