Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 9/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368315 | 1.00 | GLS (0.42) | GLSANPEPITGB3ITGA2BITGAV | |
| SCHEMBL7374249 | 0.84 | ITGB3 (0.43) | GLSITGB3ITGA2BITGAVSMN1; SMN2 | |
| SCHEMBL7373310 | 0.84 | ITGB3 (0.43) | GLSITGB3ITGA2BITGAVSMN1; SMN2 | |
| SCHEMBL7368311 | 0.79 | ANPEP (0.45) | GLSANPEPITGB3ITGA2BITGAV | |
| SCHEMBL8177121 | 0.78 | ITGB3 (0.61) | GLSANPEPITGB3ITGA2BITGAV | |
| SCHEMBL8177114 | 0.78 | ITGB3 (0.61) | GLSANPEPITGB3ITGA2BITGAV | |
| SCHEMBL7374464 | 0.67 | ITGB3 (0.41) | GLSITGB3ITGA2BITGAVITGB1 | |
| SCHEMBL7374471 | 0.67 | ITGB3 (0.41) | GLSITGB3ITGA2BITGAVITGB1 | |
| SCHEMBL7369530 | 0.66 | ITGB3 (0.41) | GLSITGB3ITGA2BITGAVITGB1 | |
| SCHEMBL7369525 | 0.66 | ITGB3 (0.41) | GLSITGB3ITGA2BITGAVITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049693-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS $g(a) v?$g(b) 3? ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2000-11-08 | — | — | EP | claimed |
| WO-1999026945-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS αvβ3 ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-06-03 | — | — | WO | claimed |
| EP-1049693-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS $g(a) v?$g(b) 3? ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999026945-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS αvβ3 ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |