Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368423 | 0.82 | CYP19A1 (0.50) | KMT2AMEN1CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL7365609 | 0.82 | CYP19A1 (0.45) | KMT2AMEN1ALDH1A1PKMRAB9A | |
| SCHEMBL7372680 | 0.81 | MAPK1 (0.48) | KDM4EKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL7372671 | 0.81 | KDM4E (0.46) | KDM4EKMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL7367075 | 0.81 | NPY5R (0.48) | KDM4EKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL7373516 | 0.80 | MKNK1 (0.58) | HTTKDM4EKMT2AALDH1A1RAB9A | |
| SCHEMBL7368881 | 0.79 | CYP11B2 (0.51) | HTTRXFP1KDM4EKMT2AMEN1 | |
| SCHEMBL7371125 | 0.78 | S1PR1 (0.48) | KMT2AMEN1MAPTGSK3B | |
| SCHEMBL7372213 | 0.77 | CYP19A1 (0.56) | KDM4EALDH1A1MAPTABCG2SMN1; SMN2 | |
| SCHEMBL7372935 | 0.77 | ALDH1A1 (0.58) | HTTRXFP1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |