Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA5A | P35218 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | GLI1 | P08151 | 1/20 | 0.55 |
| ▸ | GLI2 | P10070 | 1/20 | 0.55 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15318479 | 0.88 | CA5A (0.62) | CA1CA5ACA2TPSAB1PLG | |
| SCHEMBL10954836 | 0.88 | CA5A (0.62) | CA1CA5ACA2TPSAB1PLG | |
| SCHEMBL10954266 | 0.86 | CA5A (0.60) | CA1CA5ACA2TPSAB1PLG | |
| SCHEMBL11530575 | 0.85 | SMN1; SMN2 (0.58) | CA1CA5ACA2CYP1A2SMN1; SMN2 | |
| SCHEMBL7371177 | 0.84 | TRPV1 (0.60) | GLI1GLI2SMN1; SMN2TRPV1KDM4E | |
| SCHEMBL9136357 | 0.84 | CTSK (0.62) | TPSAB1PLGPRSS1CYP1A2CTSK | |
| Hydrochloric Acid SCHEMBL4187499 | 0.83 | TRPV1 (0.59) | GLI1GLI2SMN1; SMN2TRPV1KDM4E | |
| SCHEMBL7370487 | 0.81 | SMN1; SMN2 (0.53) | CA1CA5ACA2TPSAB1PLG | |
| SCHEMBL12294550 | 0.81 | CYP2D6 (0.62) | CA5ACA2TPSAB1PLGPRSS1 | |
| SCHEMBL30511395 | 0.81 | CA1 (0.53) | CA1CA5ACA2GLI1GLI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607394-A1 | DIPHOSPHATES OF CATECHOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994003461-A1 | DIPHOSPHATES OF CATECHOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.P.A. (IT) | 1994-02-17 | — | — | WO | disclosed |