Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372293 | 0.86 | MKNK1 (0.58) | RAF1MAPK14CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7366314 | 0.81 | MAPK13 (0.54) | RAF1MAPK14CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL2345607 | 0.79 | CYP19A1 (0.74) | CYP19A1CYP11B1CYP11B2SLC2A1ALDH1A1 | |
| SCHEMBL7365631 | 0.78 | CYP11B1 (0.53) | MAPK14CYP19A1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL7367947 | 0.78 | NPY5R (0.63) | RAF1MAPK14CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7809400 | 0.78 | CYP11B1 (0.59) | CYP19A1CYP11B1CYP11B2SLC2A1ALDH1A1 | |
| SCHEMBL4245696 | 0.76 | CYP11B1 (0.59) | CYP19A1CYP11B1CYP11B2SLC2A1ALDH1A1 | |
| SCHEMBL5031669 | 0.76 | ALDH1A1 (0.65) | CYP19A1CYP11B1CYP11B2ALDH1A1KDM4E | |
| SCHEMBL7366807 | 0.76 | NPY5R (0.59) | CYP11B1CYP11B2ALDH1A1KDM4ELMNA | |
| SCHEMBL7369244 | 0.75 | GAA (0.55) | CYP19A1CYP11B1CYP11B2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| CN-87105680-A | Imidazolium compounds and preparation method thereof and comprise the pharmaceutical composition of this compound | — | 1988-04-27 | — | — | CN | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |