Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.58 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | GLA | P06280 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | DHODH | Q02127 | 3/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.54 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.54 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.54 |
| ▸ | FHIT | P49789 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368543 | 0.86 | RAF1 (0.58) | MKNK1MKNK2KDM4EALDH1A1HPGD | |
| SCHEMBL7365631 | 0.81 | CYP11B1 (0.53) | KDM4EKMT2AALDH1A1GAADHODH | |
| SCHEMBL7367947 | 0.81 | NPY5R (0.63) | KDM4EKMT2AALDH1A1HPGDGAA | |
| SCHEMBL7366314 | 0.79 | MAPK13 (0.54) | KDM4EKMT2AALDH1A1HPGDGLA | |
| SCHEMBL1813944 | 0.77 | NPY5R (0.55) | MKNK1MKNK2KDM4EKMT2AALDH1A1 | |
| SCHEMBL7977930 | 0.77 | PIN1 (0.56) | MKNK1MKNK2KDM4EALDH1A1HPGD | |
| SCHEMBL27674584 | 0.76 | CYP11B1 (0.49) | KDM4EKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL208351 | 0.75 | MKNK1 (1.00) | MKNK1MKNK2ALDH1A1GAADHODH | |
| SCHEMBL29788154 | 0.75 | MKNK1 (1.00) | MKNK1MKNK2ALDH1A1GAADHODH | |
| SCHEMBL7375046 | 0.75 | NPY5R (0.55) | KDM4EKMT2AALDH1A1HPGDDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| CN-87105680-A | Imidazolium compounds and preparation method thereof and comprise the pharmaceutical composition of this compound | — | 1988-04-27 | — | — | CN | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |