Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | GCGR | P47871 | 4/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366319 | 0.86 | NPY5R (0.64) | NPY5RCYP19A1KDM4ENPC1RAB9A | |
| SCHEMBL7365631 | 0.86 | CYP11B1 (0.53) | NPY5RCYP19A1KDM4EALDH1A1PKM | |
| SCHEMBL7375046 | 0.85 | NPY5R (0.55) | NPY5RCYP19A1KDM4ENPC1RAB9A | |
| SCHEMBL7366314 | 0.83 | MAPK13 (0.54) | NPY5RCYP19A1KDM4ENPC1RAB9A | |
| SCHEMBL20425291 | 0.83 | MAPK13 (0.60) | CYP19A1KDM4EALDH1A1HPGDMAPK13 | |
| SCHEMBL7367787 | 0.83 | ROS1 (0.48) | NPY5RCYP19A1KDM4ENPC1RAB9A | |
| SCHEMBL13115333 | 0.82 | CYP19A1 (0.57) | NPY5RCYP19A1KDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL23736210 | 0.82 | MAPK13 (0.58) | CYP19A1KDM4EALDH1A1HPGDMAPK13 | |
| SCHEMBL7372293 | 0.81 | MKNK1 (0.58) | NPY5RCYP19A1KDM4EALDH1A1HPGD | |
| SCHEMBL7369697 | 0.81 | NPY5R (0.54) | NPY5RCYP19A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| CN-87105680-A | Imidazolium compounds and preparation method thereof and comprise the pharmaceutical composition of this compound | — | 1988-04-27 | — | — | CN | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |