Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365818 | 0.84 | SCN3A (0.46) | RAB9ASMN1; SMN2LMNAP2RX1NPC1 | |
| SCHEMBL6177517 | 0.82 | MAPT (0.42) | KMT2AMEN1RAB9AALDH1A1MAPT | |
| SCHEMBL7370817 | 0.79 | HTT (0.51) | HTTKMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL7370555 | 0.79 | NR1H4 (0.59) | SMN1; SMN2THRB | |
| SCHEMBL7368037 | 0.78 | HPGD (0.51) | HTTKMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL7368569 | 0.77 | RXFP1 (0.55) | KMT2AMEN1RAB9ACASP3NPC1 | |
| SCHEMBL7367665 | 0.77 | RAB9A (0.48) | HTTKMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL7078738 | 0.76 | ALDH1A1 (0.61) | HTTKMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL7365267 | 0.75 | HRH4 (0.55) | HTTKMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL5087407 | 0.75 | LEF1 (0.55) | KMT2AMEN1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |