Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29530470 | 0.95 | KDM4E (0.57) | ARALDH1A1GAAKDM4EPOLB | |
| SCHEMBL19527734 | 0.95 | KDM4E (0.57) | ARALDH1A1GAAKDM4EPOLB | |
| SCHEMBL1911338 | 0.91 | ALDH1A1 (0.51) | ARALDH1A1GAAKDM4EPOLB | |
| SCHEMBL29530795 | 0.91 | ALDH1A1 (0.51) | ARALDH1A1GAAKDM4EPOLB | |
| SCHEMBL7466903 | 0.86 | AR (0.46) | ARALDH1A1GAAKDM4EPOLB | |
| SCHEMBL12284280 | 0.84 | AR (0.50) | ARALDH1A1GAAKDM4EPOLB | |
| SCHEMBL6888043 | 0.84 | AR (0.47) | ARALDH1A1GAAKDM4EPOLB | |
| SCHEMBL18587828 | 0.83 | GAA (0.51) | ALDH1A1GAAKDM4EPOLBHPGD | |
| SCHEMBL973234 | 0.83 | ALDH1A1 (0.54) | ALDH1A1GAAKDM4EPOLBHPGD | |
| SCHEMBL29530857 | 0.83 | GAA (0.51) | ALDH1A1GAAKDM4EPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715612-A | SOMATOSTATIN MODULATORS AND USES THEREOF | 克林提克斯医药股份有限公司 | 2019-05-03 | — | — | CN | claimed |
| CN-104059026-B | A kind of method preparing erlotinid hydrochloride | ASYMCHEM MEDICAL GROUP (TIANJIN) INC. (CN) | 2016-03-30 | — | — | CN | claimed |
| CN-104059026-A | Preparation method for erlotinib hydrochloride | ASYMCHEM LAB TIANJIN CO LTD | 2014-09-24 | — | — | CN | claimed |
| CN-102584719-A | Preparing technology of erlotinib hydrochloride | REYOUNG PHARMACEUTICAL CO LTD | 2012-07-18 | — | — | CN | claimed |
| CN-102438995-A | Preparation process of erlotinib or pharmaceutically acceptable salt thereof | RANBAXY LAB LTD | 2012-05-02 | — | — | CN | claimed |
| CN-115108999-B | Phenyl piperazine quinazoline compound or pharmaceutically acceptable salt thereof, preparation method and application | 暨南大学 | 2023-11-03 | — | — | CN | disclosed |
| CN-114920704-B | Phenyl piperazine quinazoline compound or pharmaceutically acceptable salt thereof, preparation method and application | 暨南大学 | 2023-11-03 | — | — | CN | disclosed |
| WO-2023179366-A1 | OXADIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 星希尔生物科技(上海)有限公司 | 2023-09-28 | — | — | WO | disclosed |
| CN-115557929-A | Somatostatin modulators and uses thereof | 克林提克斯医药股份有限公司 | 2023-01-03 | — | — | CN | disclosed |
| US-11472798-B2 | Compounds | MISSION THERAPEUTICS LTD (GB) | 2022-10-18 | — | — | US | disclosed |
| CN-109715612-B | Somatostatin modulators and uses thereof | 克林提克斯医药股份有限公司 | 2022-09-16 | — | — | CN | disclosed |
| US-20220259226-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | ABBVIE INC (US) | 2022-08-18 | — | — | US | disclosed |
| WO-2007138612-A3 | A PROCESS FOR SYNTHESIS OF [6,7-BIS-(2-METHOXYETHOXY)-QUINAZOLIN-4- YL]-(3-ETHYNYLPHENYL)AMINE HYDROCHLORIDE | VITTAL MALLYA SCIENT RES FOUND (IN) | 2009-04-16 | — | — | WO | disclosed |
| WO-2007138613-A3 | A PROCESS FOR SYNTHESIS OF [6,7-BIS-(2-METHOXYETHOXY)-QUINAZOLIN-4-YL]-(3-ETHYNYLPHENYL)AMINE HYDROCHLORIDE | VITTAL MALLYA SCIENT RES FOUND (IN) | 2009-04-16 | — | — | WO | disclosed |
| WO-2007138612-A2 | A PROCESS FOR SYNTHESIS OF [6,7-BIS-(2-METHOXYETHOXY)-QUINAZOLIN-4- YL]-(3-ETHYNYLPHENYL)AMINE HYDROCHLORIDE | VITTAL MALLYA SCIENTIFIC RESEARCH FOUNDATION (IN) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007138612-A2 | A PROCESS FOR SYNTHESIS OF [6,7-BIS-(2-METHOXYETHOXY)-QUINAZOLIN-4- YL]-(3-ETHYNYLPHENYL)AMINE HYDROCHLORIDE | VITTAL MALLYA SCIENTIFIC RESEARCH FOUNDATION (IN) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007138613-A2 | A PROCESS FOR SYNTHESIS OF [6,7-BIS-(2-METHOXYETHOXY)-QUINAZOLIN-4-YL]-(3-ETHYNYLPHENYL)AMINE HYDROCHLORIDE | VITTAL MALLYA SCIENTIFIC RESEARCH FOUNDATION (IN) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007138613-A2 | A PROCESS FOR SYNTHESIS OF [6,7-BIS-(2-METHOXYETHOXY)-QUINAZOLIN-4-YL]-(3-ETHYNYLPHENYL)AMINE HYDROCHLORIDE | VITTAL MALLYA SCIENTIFIC RESEARCH FOUNDATION (IN) | 2007-12-06 | — | — | WO | disclosed |
| US-20070185160-A1 | 1-(2H)-isoquinolone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-08-09 | — | — | US | disclosed |
| EP-1724262-A1 | 1-(2H)-ISOQUINOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11472798-B2 | Compounds | UCHL1, UCHL3, UCHL5 | AR 3803/4885ALDH1A1 300/4885GAA 455/4885 |
| US-20070185160-A1 | 1-(2H)-isoquinolone derivative | NR3C2, NR1H4, NR3C1 | AR 254/4885ALDH1A1 2752/4885GAA 4558/4885 |
| US-20220259226-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | MCL1, BCL2A1, BCL2L10 | AR 2018/4885ALDH1A1 647/4885GAA 3172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.