Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.55 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27674785 | 0.87 | CYP11B1 (0.48) | NPY5RBRAFCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7366319 | 0.85 | NPY5R (0.64) | NPY5RBRAFMAPK13RAF1MAPK12 | |
| SCHEMBL7367947 | 0.85 | NPY5R (0.63) | NPY5RBRAFMAPK13RAF1MAPK12 | |
| SCHEMBL7370060 | 0.82 | ALDH1A1 (0.50) | NPY5RBRAFKMT2ACYP19A1DHODH | |
| SCHEMBL3127287 | 0.82 | MAPK13 (0.59) | BRAFMAPK13RAF1MAPK12MAPK11 | |
| SCHEMBL7369697 | 0.80 | NPY5R (0.54) | NPY5RBRAFMAPK13RAF1MAPK12 | |
| SCHEMBL7370040 | 0.80 | TUBB4A (0.48) | NPY5RBRAFCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7365631 | 0.80 | CYP11B1 (0.53) | NPY5RMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL13115329 | 0.80 | CYP11B1 (0.46) | NPY5RBRAFCYP11B1CYP11B2KMT2A | |
| SCHEMBL7366807 | 0.80 | NPY5R (0.59) | NPY5RCYP11B1CYP11B2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |