Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463979 | 0.81 | LRRK2 (0.57) | LRRK2 | |
| SCHEMBL23629116 | 0.60 | — | — | |
| SCHEMBL100765 | 0.60 | HPGDS (0.46) | — | |
| SCHEMBL24912726 | 0.57 | LTA4H (0.50) | — | |
| SCHEMBL3026407 | 0.55 | — | — | |
| SCHEMBL3901936 | 0.54 | MAPK8 (0.40) | — | |
| SCHEMBL21852154 | 0.54 | NOS3 (0.36) | — | |
| SCHEMBL28459432 | 0.54 | HPGDS (0.33) | — | |
| SCHEMBL23254437 | 0.53 | HPGDS (0.46) | LRRK2 | |
| SCHEMBL24156800 | 0.53 | ATM (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001503408-A | — | — | 2001-03-13 | — | — | JP | claimed |
| EP-0937072-A1 | THIENYLCYCLOHEXANONE DERIVATIVES AS LIGANDS OF THE GABA A? $g(a)5 RECEPTOR SUBTYPE | MERCK SHARP & DOHME LTD. (GB) | 1999-08-25 | — | — | EP | claimed |
| WO-1998018792-A1 | THIENYLCYCLOHEXANONE DERIVATIVES AS LIGANDS OF THE GABAA α5 RECEPTOR SUBTYPE | MERCK SHARP & DOHME LIMITED (GB) | 1998-05-07 | — | — | WO | claimed |