Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 11/20 | 0.49 |
| ▸ | MMP2 | P08253 | 10/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7372457 | 0.95 | MMP9 (0.45) | MMP9MMP2L3MBTL1MMP8MMP13 | |
| SCHEMBL7368355 | 0.89 | MMP9 (0.49) | MMP9MMP2L3MBTL1MMP8MMP13 | |
| Hydrochloric Acid SCHEMBL7448629 | 0.89 | MMP9 (0.48) | MMP9MMP2L3MBTL1MMP8MMP13 | |
| Hydrochloric Acid SCHEMBL7368207 | 0.89 | MMP9 (0.48) | MMP9MMP2L3MBTL1MMP8MMP13 | |
| Hydrochloric Acid SCHEMBL7369271 | 0.88 | PLAU (0.35) | MMP9MMP2MMP8MMP13ADAMTS4 | |
| Hydrochloric Acid SCHEMBL6433893 | 0.86 | PKLR (0.36) | MMP2MMP13RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL7376136 | 0.83 | PLAU (0.48) | MMP9MMP2L3MBTL1MMP13ADAMTS4 | |
| Trifluoroacetic Acid SCHEMBL7368831 | 0.83 | F2 (0.46) | MMP9MMP2L3MBTL1MMP13ADAMTS4 | |
| Hydrochloric Acid SCHEMBL7588548 | 0.81 | PLG (0.50) | MMP9MMP2MMP13ADAMTS4MMP12 | |
| SCHEMBL7368871 | 0.80 | MMP9 (0.49) | MMP9MMP2L3MBTL1MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |