Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 0.49 |
| ▸ | MMP2 | P08253 | 8/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7369278 | 0.88 | PLAU (0.36) | MMP9MMP2MMP8MMP13ADAMTS4 | |
| SCHEMBL7365021 | 0.87 | MMP2 (0.36) | MMP9MMP2L3MBTL1PLAUPLG | |
| SCHEMBL7372723 | 0.86 | MMP2 (0.35) | MMP9MMP2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7376139 | 0.83 | PLAU (0.51) | MMP9MMP2L3MBTL1MMP13ADAMTS4 | |
| Hydrochloric Acid SCHEMBL7588559 | 0.81 | PLG (0.52) | MMP9MMP2MMP13ADAMTS4MMP12 | |
| SCHEMBL7368863 | 0.80 | MMP9 (0.49) | MMP9MMP2L3MBTL1MMP8MMP13 | |
| SCHEMBL7374993 | 0.79 | PLAU (0.42) | L3MBTL1PLAUPLG | |
| SCHEMBL7370338 | 0.78 | PLAU (0.34) | PLAUPLG | |
| SCHEMBL7363440 | 0.78 | POLB (0.40) | MMP9MMP2ADAMTS4PLG | |
| SCHEMBL7368090 | 0.77 | PLAU (0.51) | PLAUPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |