Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372671 | 0.84 | KDM4E (0.46) | CYP11B2CYP11B1CYP17A1CYP19A1KMT2A | |
| SCHEMBL7367075 | 0.84 | NPY5R (0.48) | CYP11B2CYP11B1CYP19A1MEN1KMT2A | |
| SCHEMBL7370741 | 0.84 | MAPT (0.54) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL7372635 | 0.83 | CYP11B2 (0.52) | CYP11B2CYP11B1CYP17A1CYP19A1NPC1 | |
| SCHEMBL7370568 | 0.83 | CYP3A4 (0.55) | CYP11B2CYP11B1CYP17A1CYP19A1NPC1 | |
| SCHEMBL7372213 | 0.83 | CYP19A1 (0.56) | CYP11B2CYP11B1CYP19A1MAPTKDM4E | |
| SCHEMBL10567162 | 0.83 | CYP11B2 (0.45) | CYP11B2CYP11B1CYP17A1CYP19A1MEN1 | |
| SCHEMBL7373609 | 0.82 | MAPT (0.44) | CYP11B2CYP11B1CYP19A1MEN1KMT2A | |
| SCHEMBL7372230 | 0.82 | FYN (0.50) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL7370295 | 0.81 | POLB (0.52) | KDM4EALDH1A1HPGDSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| CN-87105680-A | Imidazolium compounds and preparation method thereof and comprise the pharmaceutical composition of this compound | — | 1988-04-27 | — | — | CN | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |