Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370855 | 0.86 | NPY5R (0.50) | NPY5RRAB9AKMT2AKDM4EMEN1 | |
| SCHEMBL7372671 | 0.86 | KDM4E (0.46) | NPC1RAB9AKMT2AKDM4ECYP19A1 | |
| SCHEMBL7376649 | 0.85 | POLB (0.47) | NPY5RNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL7368881 | 0.84 | CYP11B2 (0.51) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| SCHEMBL7369586 | 0.83 | ROS1 (0.47) | KDM4ELMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7371125 | 0.83 | S1PR1 (0.48) | NPY5RNPC1KMT2AMEN1CYP3A4 | |
| SCHEMBL7373516 | 0.83 | MKNK1 (0.58) | NPC1RAB9AKMT2AKDM4ELMNA | |
| SCHEMBL7372407 | 0.81 | LMNA (0.49) | NPY5RNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL7370813 | 0.81 | HTT (0.50) | RAB9AKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL7372213 | 0.80 | CYP19A1 (0.56) | KDM4ELMNACYP19A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| CN-87105680-A | Imidazolium compounds and preparation method thereof and comprise the pharmaceutical composition of this compound | — | 1988-04-27 | — | — | CN | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |