Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | FAP | Q12884 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360568 | 0.91 | DPP4 (0.36) | CCR3SLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL7367539 | 0.91 | DPP4 (0.33) | CCR3SLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL7361665 | 0.90 | GAA (0.36) | DPP4CHRM4SMN1; SMN2 | |
| SCHEMBL3258336 | 0.85 | MAOB (0.39) | CCR3SLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL3140691 | 0.85 | MAOB (0.39) | CCR3SLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL3145715 | 0.82 | MAOB (0.37) | CCR3SLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL7366933 | 0.81 | SIGMAR1 (0.33) | CCR3SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL3136103 | 0.81 | HTR1A (0.50) | MAOBHTR1AHTR7DPP4FAP | |
| SCHEMBL7364616 | 0.80 | GAA (0.39) | DPP4 | |
| SCHEMBL3129734 | 0.78 | GBA1 (0.37) | CCR3SLC6A2SLC6A4SLC6A3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |