SCHEMBL7367539 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	DPP4	P27487	2/20	0.33

▸	DPP8	Q6V1X1	1/20	0.32

▸	DPP9	Q86TI2	1/20	0.32

▸	DPP7	Q9UHL4	1/20	0.32

▸	SIGMAR1	Q99720	1/20	0.32

▸	MAOB	P27338	1/20	0.31

▸	SLC6A2	P23975	1/20	0.31

▸	SLC6A4	P31645	1/20	0.31

▸	CCR3	P51677	1/20	0.31

▸	SLC6A3	Q01959	1/20	0.31

▸	F2	P00734	1/20	0.30

▸	EPHX1	P07099	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7368940	0.91	CCR3 (0.38)	DPP4DPP8DPP9DPP7MAOB
SCHEMBL7360568	0.91	DPP4 (0.36)	DPP4MAOBSLC6A2SLC6A4CCR3
SCHEMBL7366933	0.90	SIGMAR1 (0.33)	DPP4DPP8DPP9DPP7SIGMAR1
SCHEMBL7361665	0.90	GAA (0.36)	DPP4
SCHEMBL7364616	0.80	GAA (0.39)	DPP4
SCHEMBL3140691	0.76	MAOB (0.39)	DPP4DPP8DPP9DPP7MAOB
SCHEMBL3258336	0.76	MAOB (0.39)	DPP4DPP8DPP9DPP7MAOB
SCHEMBL7434422	0.75	ALDH1A1 (0.39)	F2
SCHEMBL7359248	0.75	ALDH1A1 (0.39)	F2
SCHEMBL3145715	0.73	MAOB (0.37)	DPP4DPP8DPP9DPP7MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1997046553-A1	THROMBIN INHIBITORS	NOVARTIS AG (CH)	1997-12-11	—	—	WO	disclosed