Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364616 | 0.90 | GAA (0.39) | GAALMNADPP4CYP2C19BCHE | |
| SCHEMBL7368940 | 0.90 | CCR3 (0.38) | DPP4SMN1; SMN2CHRM4 | |
| SCHEMBL7360568 | 0.90 | DPP4 (0.36) | DPP4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7367539 | 0.90 | DPP4 (0.33) | DPP4 | |
| SCHEMBL3133531 | 0.83 | DPP4 (0.38) | GAALMNADPP4TACR1CYP2C19 | |
| SCHEMBL7366933 | 0.80 | SIGMAR1 (0.33) | GAADPP4 | |
| SCHEMBL7434422 | 0.80 | ALDH1A1 (0.39) | CYP2C19SMN1; SMN2 | |
| SCHEMBL7359248 | 0.80 | ALDH1A1 (0.39) | CYP2C19SMN1; SMN2 | |
| SCHEMBL14655322 | 0.80 | DPP4 (0.40) | DPP4TACR1CYP2C19SMN1; SMN2 | |
| SCHEMBL3138570 | 0.79 | SPHK1 (0.50) | DPP4SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |