Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373069 | 0.79 | TDP1 (0.45) | SMN1; SMN2KMT2ATDP1ALDH1A1MAPK1 | |
| SCHEMBL7367887 | 0.79 | HTT (0.47) | SMN1; SMN2KDM4EL3MBTL1HTTALDH1A1 | |
| SCHEMBL7370244 | 0.79 | SPHK2 (0.47) | KMT2A | |
| SCHEMBL7369351 | 0.78 | NPC1 (0.48) | SMN1; SMN2KDM4EL3MBTL1HTTALDH1A1 | |
| SCHEMBL7372540 | 0.78 | NPC1 (0.47) | SMN1; SMN2KDM4EHTTKMT2AALDH1A1 | |
| SCHEMBL7369285 | 0.77 | EGFR (0.48) | SMN1; SMN2KDM4EALDH1A1PKMMAPK1 | |
| SCHEMBL7868636 | 0.75 | PKM (0.73) | QPCTSMN1; SMN2KDM4EL3MBTL1HPGD | |
| SCHEMBL7369227 | 0.74 | QPCT (0.63) | QPCTSMN1; SMN2KDM4EL3MBTL1HPGD | |
| SCHEMBL7370531 | 0.73 | QPCT (0.66) | QPCTSMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL7370528 | 0.72 | QPCT (0.42) | QPCTSMN1; SMN2KDM4EL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | claimed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |