Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.35 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.35 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.35 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.35 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.35 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.35 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.35 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.35 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.35 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.35 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372987 | 0.83 | L3MBTL1 (0.36) | CYP11B1CYP11B2L3MBTL1KCNA5PSMB11 | |
| SCHEMBL7316105 | 0.76 | CYP11B1 (0.39) | CYP11B1CYP11B2PSMB11PSMD11PSMD12 | |
| SCHEMBL7316104 | 0.76 | CYP11B1 (0.39) | CYP11B1CYP11B2PSMB11PSMD11PSMD12 | |
| SCHEMBL7316112 | 0.76 | CYP11B1 (0.39) | CYP11B1CYP11B2PSMB11PSMD11PSMD12 | |
| Hydrochloric Acid SCHEMBL7285811 | 0.75 | CYP11B1 (0.43) | CYP11B1CYP11B2L3MBTL1LMNACYP1A2 | |
| SCHEMBL7320000 | 0.72 | CA1 (0.36) | CYP11B1CYP11B2LMNAHTTCYP1A2 | |
| SCHEMBL7313914 | 0.70 | CTSK (0.42) | CYP11B1CYP11B2LMNACYP1A2CYP3A4 | |
| SCHEMBL7313899 | 0.70 | CTSK (0.42) | CYP11B1CYP11B2LMNACYP1A2CYP3A4 | |
| SCHEMBL3712784 | 0.70 | ACE2 (0.39) | CYP11B1CYP11B2 | |
| SCHEMBL7326827 | 0.69 | CYP11B1 (0.38) | CYP11B1CYP11B2LMNAHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231919-A2 | N-Heterocyclic alcohol renin inhibitors | E.R. Squibb & Sons, Inc. (US) | 1987-08-12 | — | — | EP | disclosed |