Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.33 |
| ▸ | FAAH | O00519 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959378 | 0.87 | PTPN1 (0.41) | POLBHTR2BALDH1A1CYP1A1CYP1A2 | |
| SCHEMBL6959678 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1POLBCA12CA1 | |
| SCHEMBL6960622 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1POLBCA12CA1 | |
| SCHEMBL6966516 | 0.83 | GABRP (0.44) | SMN1; SMN2L3MBTL1POLBMAPTMEN1 | |
| SCHEMBL6959687 | 0.81 | POLB (0.38) | SMN1; SMN2L3MBTL1POLBABCB1FAAH | |
| SCHEMBL6954657 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1POLBCA12CA1 | |
| SCHEMBL7369564 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2L3MBTL1POLBCA12CA1 | |
| SCHEMBL6952786 | 0.81 | L3MBTL1 (0.39) | SMN1; SMN2L3MBTL1POLBCA12CA1 | |
| SCHEMBL6956148 | 0.80 | PTGES (0.45) | SMN1; SMN2L3MBTL1POLBCA12CA1 | |
| SCHEMBL6963458 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1POLBABCB1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729465-A1 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014013-A1 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |