Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 12/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.78 |
| ▸ | HPGD | P15428 | 5/20 | 0.78 |
| ▸ | MAPT | P10636 | 5/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.78 |
| ▸ | TP53 | P04637 | 3/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.78 |
| ▸ | MAOA | P21397 | 2/20 | 0.78 |
| ▸ | MAOB | P27338 | 2/20 | 0.78 |
| ▸ | BRD4 | O60885 | 1/20 | 0.78 |
| ▸ | IKBKB | O14920 | 1/20 | 0.78 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.78 |
| ▸ | RECQL | P46063 | 3/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649959 | 1.00 | TERT (1.00) | TERTKDM4ECYP3A4HPGDMAPT | |
| SCHEMBL6618127 | 0.88 | TERT (0.78) | TERTKDM4ECYP3A4HPGDMAPT | |
| SCHEMBL35318 | 0.88 | TERT (1.00) | TERTKDM4ECYP3A4HPGDMAPT | |
| 7,8-Dihydroxyflavone SCHEMBL29374601 | 0.88 | TERT (1.00) | TERTKDM4ECYP3A4HPGDMAPT | |
| 7,8-Dihydroxyflavone SCHEMBL419316 | 0.88 | TERT (1.00) | TERTKDM4ECYP3A4HPGDMAPT | |
| 7,8-Dihydroxyflavone SCHEMBL21852713 | 0.86 | TERT (0.97) | TERTKDM4ECYP3A4HPGDMAPT | |
| SCHEMBL6804531 | 0.86 | TERT (0.81) | TERTKDM4ECYP3A4HPGDMAPT | |
| SCHEMBL6615955 | 0.85 | TERT (0.74) | TERTKDM4ECYP3A4HPGDMAPT | |
| SCHEMBL7369647 | 0.85 | TERT (0.74) | TERTKDM4ECYP3A4HPGDMAPT | |
| SCHEMBL5309179 | 0.84 | TERT (0.73) | TERTKDM4ECYP3A4HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038971-A1 | OLIGONUCLEOTIDES CONTAINING A LIGAND AT A NUCLEOBASE, 2' POSITION, OR 3' POSITION | ADARX PHARMACEUTICALS, INC. (US) | 2025-02-20 | — | — | WO | claimed |
| WO-2025038971-A1 | OLIGONUCLEOTIDES CONTAINING A LIGAND AT A NUCLEOBASE, 2' POSITION, OR 3' POSITION | ADARX PHARMACEUTICALS, INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| WO-2025038960-A1 | OLIGONUCLEOTIDES CONTAINING A LIGAND AT AN INTERNAL POSITION | ADARX PHARMACEUTICALS, INC. (US) | 2025-02-20 | — | — | WO | disclosed |