Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368822 | 0.93 | GPR119 (0.52) | HTR1ADRD2HTR2ADRD3GPR119 | |
| SCHEMBL7365434 | 0.92 | GPR119 (0.53) | HTR1ADRD2HTR2ADRD3GPR119 | |
| SCHEMBL7365650 | 0.88 | HTR1A (0.45) | HTR1ADRD2HTR2ADRD3GPR119 | |
| SCHEMBL7365804 | 0.84 | GPR119 (0.56) | GPR119 | |
| SCHEMBL7358222 | 0.83 | GPR119 (0.51) | DRD2DRD3GPR119TGFBR1 | |
| Hydrochloric Acid SCHEMBL8477389 | 0.83 | ATM (0.42) | HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL8473421 | 0.82 | GPR119 (0.53) | HTR1ADRD2HTR2ADRD3GPR119 | |
| SCHEMBL7360486 | 0.81 | GPR119 (0.44) | GPR119 | |
| SCHEMBL4523959 | 0.81 | GPR119 (0.56) | HTR1ADRD2HTR2ADRD3GPR119 | |
| SCHEMBL7363095 | 0.80 | GPR119 (0.46) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |