Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364915 | 0.89 | GPR119 (0.45) | GPR119NPSR1FAAH | |
| SCHEMBL7368822 | 0.87 | GPR119 (0.52) | GPR119NPSR1ATM | |
| SCHEMBL7365804 | 0.86 | GPR119 (0.56) | GPR119NPSR1ATM | |
| Hydrochloric Acid SCHEMBL7368478 | 0.84 | NPSR1 (0.44) | NPSR1ATMMETAP1 | |
| SCHEMBL7360486 | 0.83 | GPR119 (0.44) | GPR119NPSR1 | |
| SCHEMBL12814098 | 0.81 | NPSR1 (0.55) | GPR119NPSR1ATMMETAP1 | |
| SCHEMBL13757809 | 0.81 | GPR119 (0.65) | GPR119 | |
| SCHEMBL8477292 | 0.80 | YAP1 (0.42) | GPR119 | |
| SCHEMBL7362867 | 0.80 | YAP1 (0.42) | GPR119 | |
| SCHEMBL7369686 | 0.80 | HTR1A (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |