Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368822 | 0.88 | GPR119 (0.52) | HTR1ADRD2HTR2ADRD3GPR119 | |
| SCHEMBL7369686 | 0.88 | HTR1A (0.47) | HTR1ADRD2HTR2ADRD3GPR119 | |
| SCHEMBL7365434 | 0.87 | GPR119 (0.53) | HTR1ADRD2HTR2ADRD3GPR119 | |
| Hydrochloric Acid SCHEMBL7365760 | 0.85 | MAPK1 (0.39) | HTR1ADRD2HTR2ADRD3ALDH1A1 | |
| SCHEMBL7365804 | 0.79 | GPR119 (0.56) | GPR119 | |
| SCHEMBL7360486 | 0.79 | GPR119 (0.44) | GPR119ALDH1A1 | |
| SCHEMBL7358222 | 0.78 | GPR119 (0.51) | DRD2DRD3GPR119ALDH1A1 | |
| SCHEMBL8226185 | 0.78 | L3MBTL1 (0.55) | GPR119ALDH1A1TSHRMAPK1 | |
| SCHEMBL7363095 | 0.77 | GPR119 (0.46) | GPR119 | |
| SCHEMBL7363614 | 0.76 | GPR119 (0.46) | DRD2DRD3GPR119ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |