Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | CTSE | P14091 | 1/20 | 0.45 |
| ▸ | PGC | P20142 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371915 | 1.00 | REN (0.53) | RENKLK5CTSDCTSEPGC | |
| SCHEMBL8712611 | 0.85 | REN (0.53) | RENKLK5CTSDCTSEPGC | |
| SCHEMBL8712609 | 0.85 | REN (0.53) | RENKLK5CTSDCTSEPGC | |
| SCHEMBL7374902 | 0.85 | REN (0.43) | RENKLK5 | |
| SCHEMBL7371572 | 0.85 | REN (0.43) | RENKLK5 | |
| SCHEMBL30318981 | 0.84 | REN (0.58) | RENKLK5 | |
| SCHEMBL5220702 | 0.84 | REN (0.58) | RENKLK5 | |
| SCHEMBL7408240 | 0.81 | CTSD (0.61) | RENKLK5CTSDCTSEPGC | |
| SCHEMBL6449191 | 0.81 | CTSD (0.61) | RENKLK5CTSDCTSEPGC | |
| SCHEMBL6449190 | 0.81 | CTSD (0.61) | RENKLK5CTSDCTSEPGC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708760-A1 | CYCLIC HYDRAZINE COMPOUNDS | Novartis AG (CH) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002582-A1 | CYCLIC HYDRAZINE COMPOUNDS | CIBA-GEIGY AG (CH) | 1995-01-26 | — | — | WO | disclosed |