Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 11/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | CTSE | P14091 | 1/20 | 0.45 |
| ▸ | PGC | P20142 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712611 | 1.00 | REN (0.53) | RENKLK5PSEN1PSEN2APH1B | |
| SCHEMBL8709813 | 0.90 | REN (0.43) | RENKLK5PSEN1PSEN2APH1B | |
| SCHEMBL8709818 | 0.90 | REN (0.43) | RENKLK5PSEN1PSEN2APH1B | |
| SCHEMBL8712293 | 0.90 | REN (0.43) | RENKLK5PSEN1PSEN2APH1B | |
| SCHEMBL8709243 | 0.88 | REN (0.42) | RENKLK5ATMKMT2A | |
| SCHEMBL8709246 | 0.88 | REN (0.42) | RENKLK5ATMKMT2A | |
| SCHEMBL8711623 | 0.88 | REN (0.42) | RENKLK5ATMKMT2A | |
| SCHEMBL8709237 | 0.85 | REN (0.51) | REN | |
| SCHEMBL7371915 | 0.85 | REN (0.53) | RENKLK5CTSDCTSEPGC | |
| SCHEMBL7370041 | 0.85 | REN (0.53) | RENKLK5CTSDCTSEPGC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |