Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 13/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374902 | 1.00 | REN (0.43) | RENKLK5ATMKMT2AMEN1 | |
| SCHEMBL7370041 | 0.85 | REN (0.53) | RENKLK5 | |
| SCHEMBL7371915 | 0.85 | REN (0.53) | RENKLK5 | |
| SCHEMBL7411855 | 0.84 | CTSD (0.45) | RENKLK5ATMKMT2A | |
| SCHEMBL7411853 | 0.84 | CTSD (0.45) | RENKLK5ATMKMT2A | |
| SCHEMBL8916903 | 0.84 | CTSD (0.45) | RENKLK5ATMKMT2A | |
| SCHEMBL8712611 | 0.75 | REN (0.53) | RENKLK5ATMKMT2A | |
| SCHEMBL8712609 | 0.75 | REN (0.53) | RENKLK5ATMKMT2A | |
| SCHEMBL10774694 | 0.73 | REN (0.43) | RENKLK5 | |
| SCHEMBL8708822 | 0.72 | REN (0.41) | RENKLK5ATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708760-A1 | CYCLIC HYDRAZINE COMPOUNDS | Novartis AG (CH) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002582-A1 | CYCLIC HYDRAZINE COMPOUNDS | CIBA-GEIGY AG (CH) | 1995-01-26 | — | — | WO | disclosed |