Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.59 |
| ▸ | MMP13 | P45452 | 12/20 | 0.59 |
| ▸ | MMP9 | P14780 | 11/20 | 0.59 |
| ▸ | MMP3 | P08254 | 11/20 | 0.59 |
| ▸ | MMP7 | P09237 | 10/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12479656 | 0.85 | MMP1 (0.79) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL7370308 | 0.79 | MMP1 (0.74) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL7414596 | 0.79 | MMP1 (0.59) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL7685731 | 0.79 | MMP1 (0.58) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL7685735 | 0.79 | MMP1 (0.58) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL7375156 | 0.78 | MMP1 (0.77) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL3825843 | 0.76 | HCRTR1 (0.53) | TP53 | |
| SCHEMBL7683254 | 0.76 | MMP1 (0.64) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL28019708 | 0.75 | MMP1 (0.66) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL6906972 | 0.74 | MMP1 (0.79) | MMP1MMP13MMP9MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923563-A1 | 1,4-HETEROCYCLIC METALLPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008825-A1 | 1,4-HETEROCYCLIC METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |