Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.34 |
| ▸ | CCR1 | P32246 | 5/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | ITGA2 | P17301 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924872 | 0.85 | ITGB3 (0.40) | ALDH1A1MAPTITGB3ITGA2BCCR1 | |
| SCHEMBL7370446 | 0.84 | PREP (0.38) | ALDH1A1MAPTITGB3ITGA2BLMNA | |
| Trifluoroacetic Acid SCHEMBL7366990 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BCCR1ITGA2LMNA | |
| SCHEMBL7924876 | 0.68 | ITGB3 (0.49) | ITGB3ITGA2BITGA2KMT2A | |
| SCHEMBL7924873 | 0.68 | ITGB3 (0.49) | ITGB3ITGA2BITGA2KMT2A | |
| SCHEMBL7364293 | 0.67 | DPP8 (0.41) | ALDH1A1ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7931567 | 0.66 | ITGB3 (0.49) | ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7370443 | 0.66 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL7372732 | 0.63 | ITGB3 (0.43) | ITGB3ITGA2BKMT2A | |
| SCHEMBL7372733 | 0.63 | ITGB3 (0.43) | ITGB3ITGA2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970071-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998039324-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-11 | — | — | WO | disclosed |