Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 4/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26654648 | 0.88 | P2RX7 (0.50) | KDM4EL3MBTL1KDM4ARAB9AEGLN1 | |
| SCHEMBL15328824 | 0.85 | SLC40A1 (0.56) | PREPKDM4EL3MBTL1KDM4ARAB9A | |
| SCHEMBL15328529 | 0.83 | KDM4E (0.49) | PREPKDM4EL3MBTL1KDM4ARAB9A | |
| SCHEMBL4519716 | 0.81 | KDM4E (0.68) | PREPKDM4EL3MBTL1KDM4ARAB9A | |
| Hydrochloric Acid SCHEMBL15328531 | 0.80 | KDM4E (0.66) | PREPKDM4EL3MBTL1KDM4ARAB9A | |
| SCHEMBL7377364 | 0.79 | PSMD14 (0.68) | PREPKDM4EL3MBTL1KDM4ARAB9A | |
| SCHEMBL8185833 | 0.77 | KMT2A (0.63) | P2RX7KMT2AMEN1MAPT | |
| SCHEMBL7369890 | 0.75 | NUDT1 (0.52) | KDM4EL3MBTL1KDM4ARAB9AEGLN1 | |
| SCHEMBL4492459 | 0.75 | P2RX7 (0.63) | PREPP2RX7ADORA2A | |
| SCHEMBL5603305 | 0.74 | NSD2 (0.56) | PREPKDM4EP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | disclosed |
| EP-1003737-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS HFGAN72 ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999009024-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS HFGAN72 ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1999-02-25 | — | — | WO | disclosed |