Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364513 | 0.88 | KDM4E (0.59) | HRH3KDM4ELTA4H | |
| SCHEMBL7371432 | 0.81 | KDM4E (0.62) | MEN1KMT2AHRH3KDM4E | |
| SCHEMBL7368858 | 0.79 | HRH3 (0.52) | HRH3KDM4ELTA4H | |
| SCHEMBL7370485 | 0.78 | MAPT (0.54) | KMT2AHRH3KDM4ELTA4H | |
| SCHEMBL7906481 | 0.77 | SMN1; SMN2 (0.62) | MEN1KMT2AHRH3KDM4ELTA4H | |
| SCHEMBL7373567 | 0.77 | SMN1; SMN2 (0.62) | MEN1KMT2AHRH3KDM4ELTA4H | |
| SCHEMBL14970686 | 0.77 | LTA4H (0.87) | MEN1KMT2AHRH3LTA4HPTGS2 | |
| SCHEMBL5438744 | 0.77 | LTA4H (0.87) | MEN1KMT2AHRH3LTA4HPTGS2 | |
| SCHEMBL7383210 | 0.76 | ALDH1A1 (0.64) | MEN1KMT2AHRH3KDM4ELTA4H | |
| SCHEMBL28285426 | 0.76 | HRH3 (0.88) | MEN1KMT2AHRH3LTA4HPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057332-A | Substituted 1,4-dihydropyrimidine-5-carboxylate compounds, their preparation and uses | ASTRA AKTIEBOLAG (SE) | 2000-05-02 | — | — | US | disclosed |
| EP-0994859-A1 | COMPOUNDS | Astra Aktiebolag (publ) (SE) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001437-A1 | COMPOUNDS | ASTRA AKTIEBOLAG (PUBL) (SE) | 1999-01-14 | — | — | WO | disclosed |