Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CBFB | Q13951 | 7/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.45 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 5/20 | 0.43 |
| ▸ | METAP1 | P53582 | 5/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565904 | 0.83 | SMN1; SMN2 (0.48) | GAANPC1PKMRAB9AALDH1A1 | |
| SCHEMBL7372784 | 0.78 | MAPK14 (0.65) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL7369715 | 0.75 | CYP11B1 (0.52) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL4766017 | 0.75 | KDM4E (0.46) | NPC1PKMRAB9AALDH1A1L3MBTL1 | |
| SCHEMBL9385179 | 0.73 | METAP2 (0.54) | GAANPC1PKMRAB9AALDH1A1 | |
| SCHEMBL1780998 | 0.72 | KDM4E (0.56) | NPC1PKMRAB9AALDH1A1L3MBTL1 | |
| SCHEMBL6451131 | 0.71 | SMN1; SMN2 (0.69) | NPC1PKMRAB9AALDH1A1L3MBTL1 | |
| SCHEMBL6763113 | 0.70 | L3MBTL1 (0.44) | NPC1PKMRAB9AALDH1A1L3MBTL1 | |
| SCHEMBL17810407 | 0.69 | KDM4E (0.54) | GAANPC1PKMRAB9AALDH1A1 | |
| SCHEMBL29914907 | 0.68 | KDM4E (0.46) | NPC1PKMRAB9AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| CN-87105680-A | Imidazolium compounds and preparation method thereof and comprise the pharmaceutical composition of this compound | — | 1988-04-27 | — | — | CN | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |