Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | METAP1 | P53582 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763113 | 0.80 | L3MBTL1 (0.44) | KDM4EMETAP1LMNACCR1CCR5 | |
| SCHEMBL4766148 | 0.80 | KDM4E (0.67) | KDM4ELMNAHIF1ASMN1; SMN2HTT | |
| SCHEMBL24589288 | 0.80 | HTT (0.43) | KDM4EMETAP1LMNACCR1CCR5 | |
| SCHEMBL7370953 | 0.75 | MGAM (0.49) | KDM4EMETAP1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL9385179 | 0.73 | METAP2 (0.54) | KDM4EMETAP1LMNAHIF1ASMN1; SMN2 | |
| SCHEMBL5850257 | 0.72 | KDM4E (0.68) | KDM4ELMNACYP1A2POLBSMN1; SMN2 | |
| SCHEMBL15996311 | 0.72 | KDM4E (0.48) | KDM4EMETAP1LMNACCR1CCR5 | |
| SCHEMBL17810407 | 0.71 | KDM4E (0.54) | KDM4EMETAP1LMNAHIF1ASMN1; SMN2 | |
| SCHEMBL24427583 | 0.71 | HIF1A (0.38) | KDM4ECCR1CCR5CCR8POLB | |
| SCHEMBL14341067 | 0.70 | KDM4E (0.56) | KDM4EMETAP1LMNACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135365-A1 | DISUBSTITUTED CYCLOPENTANE KINASE INHIBITORS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) | 2022-06-30 | — | — | WO | disclosed |
| US-20120122212-A1 | TGF-BETA PATHWAY INHIBITORS FOR ENHANCEMENT OF CELLULAR REPROGRAMMING OF HUMAN CELLS | IPIERIAN, INC. | 2012-05-17 | — | — | US | disclosed |