Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.71 |
| ▸ | CA9 | Q16790 | 14/20 | 0.71 |
| ▸ | CA12 | O43570 | 12/20 | 0.71 |
| ▸ | CA1 | P00915 | 12/20 | 0.71 |
| ▸ | CA7 | P43166 | 7/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.71 |
| ▸ | CA6 | P23280 | 5/20 | 0.71 |
| ▸ | CA5A | P35218 | 5/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.71 |
| ▸ | CA4 | P22748 | 3/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL2215151 | 0.87 | CA2 (0.77) | CA2CA9CA12CA1CA7 | |
| Sulfanilamide SCHEMBL27364276 | 0.87 | CA2 (0.85) | CA2CA9CA12CA1CA7 | |
| Sulfanilamide SCHEMBL28206802 | 0.87 | CA2 (0.94) | CA2CA9CA12CA1CA7 | |
| Sulfanilamide SCHEMBL419065 | 0.85 | CA2 (0.74) | CA2CA9CA12CA1CA7 | |
| Sulfanilamide SCHEMBL4188099 | 0.84 | CA2 (0.90) | CA2CA9CA12CA1CA7 | |
| Sulfanilamide SCHEMBL2798899 | 0.84 | CA2 (1.00) | CA2CA9CA12CA1CA7 | |
| Sulfanilamide SCHEMBL31544839 | 0.84 | CA2 (1.00) | CA2CA9CA12CA1CA7 | |
| Sulfanilamide SCHEMBL740 | 0.84 | CA2 (1.00) | CA2CA9CA12CA1CA7 | |
| Sulfanilamide SCHEMBL30659052 | 0.84 | CA2 (1.00) | CA2CA9CA12CA1CA7 | |
| Sulfanilamide SCHEMBL28201481 | 0.82 | CA2 (0.85) | CA2CA9CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338029-B2 | Negative electrode active material for nonaqueous electrolyte battery, nonaqueous electrolyte battery, battery pack, and vehicle | KABUSHIKI KAISHA TOSHIBA (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20120135294-A1 | NEGATIVE ELECTRODE ACTIVE MATERIAL FOR NONAQUEOUS ELECTROLYTE BATTERY, NONAQUEOUS ELECTROLYTE BATTERY, BATTERY PACK, AND VEHICLE | HARADA YASUHIRO (JP) | 2012-05-31 | — | — | US | disclosed |
| US-8137843-B2 | Negative electrode active material for nonaqueous electrolyte battery, nonaqueous electrolyte battery, battery pack, and vehicle | KABUSHIKI KAISHA TOSHIBA (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20080078594-A1 | NEGATIVE ELECTRODE ACTIVE MATERIAL FOR NONAQUEOUS ELECTROLYTE BATTERY, NONAQUEOUS ELECTROLYTE BATTERY, BATTERY PACK, AND VEHICLE | KABUSHIKI KAISHA TOSHIBA (JP) | 2008-04-03 | — | — | US | disclosed |