Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.74 |
| ▸ | CA9 | Q16790 | 13/20 | 0.74 |
| ▸ | CA1 | P00915 | 12/20 | 0.74 |
| ▸ | CA12 | O43570 | 11/20 | 0.74 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.74 |
| ▸ | CA7 | P43166 | 6/20 | 0.74 |
| ▸ | CA6 | P23280 | 5/20 | 0.74 |
| ▸ | CA5A | P35218 | 5/20 | 0.74 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.74 |
| ▸ | CA4 | P22748 | 4/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL7766519 | 0.91 | CA2 (0.61) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL629179 | 0.89 | CA2 (0.77) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL2215151 | 0.89 | CA2 (0.77) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL28201481 | 0.89 | CA2 (0.85) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL28616095 | 0.86 | CA2 (0.90) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL4188099 | 0.86 | CA2 (0.90) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL30659052 | 0.86 | CA2 (1.00) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL2798899 | 0.86 | CA2 (1.00) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL740 | 0.86 | CA2 (1.00) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL31544839 | 0.86 | CA2 (1.00) | CA2CA9CA1CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117844190-A | Graphene/epoxy resin composite material with high heat conduction electromagnetic shielding performance, and preparation method and application thereof | 湖北工业大学 | 2024-04-09 | — | — | CN | claimed |
| US-20090181932-A1 | COMPOSITIONS CONTAINING O-SULFATE AND O-PHOSPHATE CONTAINING ARYL SULFONAMIDE DERIVATIVES USEFUL AS beta-AMYLOID INHIBITORS | WYETH (US) | 2009-07-16 | — | — | US | claimed |
| WO-2009089237-A1 | COMPOSITIONS CONTAINING O-SULFATE AND O-PHOSPHATE CONTAINING ARYL SULFONAMIDE DERIVATIVES USEFUL AS BETA-AMYLOID INHIBITORS | WYETH (US) | 2009-07-16 | — | — | WO | claimed |
| CN-1443525-A | Composite containing siloxane, compound with ester group and copolymer and its application method | OREAL (FR) | 2003-09-24 | — | — | CN | claimed |
| EP-0970135-A1 | TRANSPARENT FLUORINATED POLYURETHANE COATING COMPOSITIONS AND METHODS OF USE THEREOF | Pilkington Aerospace Inc. (US) | 2000-01-12 | — | — | EP | claimed |
| US-5880089-A | RINSE AID CONSISTS OF A FLUORINATED HYDROCARBON NONIONIC SURFACTANT, A POLYOXYALKYLENE OXIDE MODIFIED WITH POLYDIMETHYLSILOXANE OR POLYBETAINE MODIFIED POLYSILOXANE AND A NONIONIC BLOCK COPOLYMER OF ETHYLENE OXIDE-PROPYLENE OXIDE | ECOLAB INC. (US) | 1999-03-09 | — | — | US | claimed |
| EP-0875556-A2 | Rinse aid for plasticware | ECOLAB INC. (US) | 1998-11-04 | — | — | EP | claimed |
| WO-1998044015-A1 | TRANSPARENT FLUORINATED POLYURETHANE COATING COMPOSITIONS AND METHODS OF USE THEREOF | PILKINGTON AEROSPACE INC. (US) | 1998-10-08 | — | — | WO | claimed |
| EP-0781322-B1 | RINSE AID FOR PLASTICWARE | ECOLAB INC (US) | 1998-07-08 | — | — | EP | claimed |
| EP-0781322-A1 | RINSE AID FOR PLASTICWARE | ECOLAB INC. (US) | 1997-07-02 | — | — | EP | claimed |
| US-5603776-A | USING A POLYETHERSILOXANE COPOLYMER, FLUORINATED HYDROCARBON AND A NONIONIC SURFACTANTS | ECOLAB INC. (US) | 1997-02-18 | — | — | US | claimed |
| WO-1996008553-A1 | RINSE AID FOR PLASTICWARE | ECOLAB INC. (US) | 1996-03-21 | — | — | WO | claimed |
| CN-117844190-A | Graphene/epoxy resin composite material with high heat conduction electromagnetic shielding performance, and preparation method and application thereof | 湖北工业大学 | 2024-04-09 | — | — | CN | disclosed |
| US-20230174562-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | Tonix Pharmaceuticals, Inc. | 2023-06-08 | — | — | US | disclosed |
| US-20230138150-A1 | RADIO-PROTECTIVE AND CHEMO-PROTECTIVE SUBSTITUTED THIOLS | Tonix Pharmaceuticals, Inc. | 2023-05-04 | — | — | US | disclosed |
| CN-115968372-A | Radioprotective and chemoprotective compounds | 通尼克斯医药有限公司 | 2023-04-14 | — | — | CN | disclosed |
| US-4877809-A | ANTITHROMBOTIC AGENTS | CL PHARMA AKTIENGESELLSCHAFT (AT) | 1989-10-31 | — | — | US | disclosed |
| US-4256625-A | PERFLUOROALKENYLOXY, N-PHOSPHATOALKYL-SULFAMOYL-BENZENE SURFACTANT | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1981-03-17 | — | — | US | disclosed |
| EP-0007206-A1 | Phenethanolamines, their formulations, preparation and use | ELI LILLY AND COMPANY (US) | 1980-01-23 | — | — | EP | disclosed |
| US-4163855-A | Azetidine compounds and process for production | PHILIP MORRIS INCORPORATED (US) | 1979-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174562-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | MGMT, RCOR3, TSPO | CA2 4227/4885CA9 1514/4885CA1 2011/4885 |
| US-20230138150-A1 | RADIO-PROTECTIVE AND CHEMO-PROTECTIVE SUBSTITUTED THIOLS | MGMT, GSTA1, GSTP1 | CA2 2254/4885CA9 716/4885CA1 192/4885 |
| US-20090181932-A1 | COMPOSITIONS CONTAINING O-SULFATE AND O-PHOSPHATE CONTAINING ARYL SULFONAMIDE DERIVATIVES USEFUL AS beta-AMYLOID INHIBITORS | SCN3A, HCN3, KCNN3 | CA2 39/4885CA9 1151/4885CA1 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.