Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.31 |
| ▸ | KYNU | Q16719 | 2/20 | 0.30 |
| ▸ | ALPI | P09923 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375800 | 0.82 | IDO1 (0.36) | IDO1TDO2PTGS1SLC7A11ALPI | |
| SCHEMBL7200966 | 0.81 | IDO1 (0.36) | IDO1TDO2PTGS1SLC7A11ALPI | |
| SCHEMBL15156025 | 0.79 | IDO1 (0.35) | IDO1TDO2PTGS1SLC7A11ALPI | |
| SCHEMBL1614569 | 0.79 | IDO1 (0.35) | IDO1TDO2PTGS1SLC7A11ALPI | |
| SCHEMBL7241021 | 0.79 | IDO1 (0.35) | IDO1TDO2PTGS1SLC7A11ALPI | |
| SCHEMBL4458615 | 0.78 | IDO1 (0.37) | IDO1TDO2PTGS1SLC7A11ALPI | |
| SCHEMBL5816605 | 0.75 | GRIN2D (0.37) | — | |
| SCHEMBL686409 | 0.75 | IDO1 (0.33) | PMP22IDO1TDO2PTGS1SLC7A11 | |
| SCHEMBL687402 | 0.75 | IDO1 (0.33) | PMP22IDO1TDO2PTGS1SLC7A11 | |
| SCHEMBL7591393 | 0.75 | IDO1 (0.33) | PMP22IDO1TDO2PTGS1SLC7A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670479-A | α-ketoamide derivatives as inhibitors of thrombosis | CORVAS INTERNATIONAL, INC. (US) | 1997-09-23 | — | — | US | disclosed |
| US-5656600-A | MODIFIED POLYPEPTIDES | CORVAS INTERNATIONAL, INC. (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0693083-A4 | ALPHA-KETOAMIDE DERIVATIVES AS INHIBITORS OF THROMBOSIS | CORVAS INT INC (US) | 1996-07-17 | — | — | EP | disclosed |
| EP-0693083-A1 | ALPHA-KETOAMIDE DERIVATIVES AS INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994021673-A1 | ALPHA-KETOAMIDE DERIVATIVES AS INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1994-09-29 | — | — | WO | disclosed |